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Bad Immunity Genes - Why do They Survive? New evidence has been discovered by biologists at the University of Utah as to why people, mice and other vertebrate animals carry thousands of different genes to create major histocompatibility complex (MHCs) proteins, despite the fact that some of those genes make humans vulnerable to autoimmune diseases and infections. Findings from the study will be published online the week of February 6, 2012, in the journal Proceedings of the National Academy of Sciences. MHC proteins are found on the surface of most cells in vertebrates and define an individual's tissue type... Green Tea Protects Against Functional Disability Linked To Aging Regular green tea drinkers have a lower risk of developing functional disability, researchers from Tohoku University Graduate School of Medicine, Sendai, Japan, reported in the American Journal of Clinical Nutrition. Functional disability refers to problems with daily chores and activities, such as bathing or dressing. As background information, the authors explained that prior studies had found that consuming green tea reduced the risk of diseases associated with functional disability, such as osteoporosis, cognitive impairment and stroke... Merck Has Positive Results With New Insomnia Drug Merck has announced positive results in a phase 3 trial of its insomnia drug. It's a key player in the companies up and coming products, especially considering the loss of patent protection on its top drugs for asthma and allergys. The experimental drug known as suvorexant, uses a new mechanism created to help people sleep, but at the same time aiming to mitigate side effects associated with popular sleep aids. Analysts think that annual sales of the drug could top $500 million within several years. Peter S... Child Abuse - 4,569 Hospitalizations And 300 Deaths In One Year, USA Child abuse injuries resulted in 4,500 hospitalizations and 300 fatalities in just one year in the USA, researchers from Yale School of Medicine reported in the journal Pediatrics. This is the first study that has quantified abuse severity and how many children ended up in hospital, the authors added. Child Protective Services had only tracked occurrence of child abuse at a national level. Dr. John M. Leventhal and team set out to find out what the incidence of hospitalizations due to child abuse among children under 18 years of age might be... Lung Function At School Age Better Thanks To Breastfeeding A study by researchers in Switzerland and the UK reveals that breastfeeding is linked to enhanced lung function at school age, especially in children born to asthmatic mothers. The study is published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. Claudia E. Kuehni, M.D... Teen Secondhand Smoke Exposure Down, But Not Enough Secondhand Smoke (SHS) exposure among middle and high school students in the USA has dropped over the last ten years, researchers from the National Center for Chronic Disease Prevention and Health Promotion and the CDC (Centers for Disease Control and Prevention) reported in the March edition of Pediatrics. The authors explained that passengers in cars who accompany smokers run significant health risks, especially if they are children and teenagers. Even though exposure has gone down over the last decade, 22... Trevo® Pro System - Good Results In Restoring Function In Stroke Patients Stryker has just announced the results of the TREVO Study at the International Stroke Conference in New Orleans. TREVO, (Thrombectomy REvascularization of large Vessel Occlusions in acute ischemic stroke) was designed to evaluate Trevo® System's ability to remove the blood clots that cause strokes, restoring the blood flow to the brain, and was one of the first prospective multi-center clinical studies of clot-removing stent retriever technology. The study involved sixty patients at seven leading European stroke centers. An independent core lab measured revascularization... Somatosensory Neurons Remain Overactive After Exposure To Loud Noises It is common knowledge that it takes a while for the hearing to become 'normal' again after listening to music that is too loud. The American Tinnitus Association estimates that there are almost 50 million people in the U.S. and millions more worldwide who suffer from tinnitus, which can range from being intermittent and mildly annoying to chronic, severe and debilitating. There is no cure for tinnitus... Disturbing Rates Of Child Abuse And Hospitalizations In one year alone, over 4,500 children in the United States were hospitalized due to child abuse, and 300 of them died of their injuries, Yale School of Medicine researchers report in a new study. The findings are published in the March 2012 issue of Pediatrics (published online Feb. 6). Several measures have been used to track the national occurrence of child abuse, including data from Child Protective Services. But until now none quantified the severity of the abuse or whether the child was hospitalized as a result. Led by John M. Leventhal, M.D... Controlling Gene Expression With New RNA-Based Therapeutic Strategies Small RNA-based nucleic acid drugs represent a promising new class of therapeutic agents for silencing abnormal or overactive disease-causing genes, and researchers have discovered new mechanisms by which RNA drugs can control gene activity. A comprehensive review article in Nucleic Acid Therapeutics, a peer-reviewed journal published by Mary Ann Liebert, Inc., details these advances. Short strands of nucleic acids, called small RNAs, can be used for targeted gene silencing, making them attractive drug candidates... Football Findings Suggest Concussions Caused By Series Of Hits A two-year study of high school football players suggests that concussions are likely caused by many hits over time and not from a single blow to the head, as commonly believed. Purdue University researchers have studied football players for two seasons at Jefferson High School in Lafayette, Ind., where 21 players completed the study the first season and 24 the second season, including 16 repeating players. Helmet-sensor impact data from each player were compared with brain-imaging scans and cognitive tests performed before, during and after each season... Cause Of Metabolic Disease Identified By Whole Exome Sequencing Sequencing a patient's entire genome to discover the source of his or her disease is not routine - yet. But geneticists are getting close. A case report, published this week in the American Journal of Human Genetics, shows how researchers can combine a simple blood test with an "executive summary" scan of the genome to diagnose a type of severe metabolic disease. Researchers at Emory University School of Medicine and Sanford-Burnham Medical Research Institute used "whole-exome sequencing" to find the mutations causing a glycosylation disorder in a boy born in 2004... Temporary Stent Procedure Improves Stroke Recovery A new way of opening blocked arteries in the brain using a removable stent system in people suffering strokes brought remarkably positive results in how those patients recovered from the strokes, according to a study presented at the American Stroke Association's annual conference in New Orleans. The interventional procedure was performed on more than 140 stroke patients at 18 medical centers throughout the United States... Insight Into Cell Aging Likely Following Discovery Of Extremely Long-Lived Proteins One of the big mysteries in biology is why cells age. Now scientists at the Salk Institute for Biological Studies report that they have discovered a weakness in a component of brain cells that may explain how the aging process occurs in the brain. The scientists discovered that certain proteins, called extremely long-lived proteins (ELLPs), which are found on the surface of the nucleus of neurons, have a remarkably long lifespan... Weight Management Programs For African-American Women Are More Successful If Held In A Church As a brand new year gets underway, people all over America are resolving to better manage their weight and have a more healthy 2012. According to a new study, those starting new weight loss programs may be surprised to find out that both location and level of experience may influence their success... Brain Tumor Eradication And Prolonged Survival Tocagen Inc. has announced the publication of data showing the company's investigational treatment for high grade glioma eradicates brain tumors and provides a dramatic survival benefit in mouse models of glioblastoma. Almost all mice receiving the top dose of Toca 511 followed by 5-FC were still alive at 180 days, which was the termination date for the experiment, whereas all control mice died by day 43. The article was published in the February issue of the Neuro-Oncology journal... The Risk Of Colon Cancer Could Be Reduced By Regular Use Of Vitamin And Mineral Supplements Could the use of vitamin and mineral supplements in a regular diet help to reduce the risk of colon cancer and protect against carcinogens? A study published in the Canadian Journal of Physiology and Pharmacology (CJPP) found that rats given regular multivitamin and mineral supplements showed a significantly lower risk of developing colon cancer when they were exposed to carcinogens. "It has been unclear whether multivitamin supplementation to cancer patients is helpful, has no effect, or is even detrimental during therapy," commented Dr. Grant Pierce, Editor of CJPP... Within Weeks Of Smoking Cessation, Coughing And Other Respiratory Symptoms Improve If the proven long-term benefits of smoking cessation are not enough to motivate young adults to stop smoking, a new study shows that 18- to 24-year olds who stop smoking for at least two weeks report substantially fewer respiratory symptoms, especially coughing. The study findings are detailed in Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal published by Mary Ann Liebert, Inc. The article is available online... New Device Removes Stroke-Causing Blood Clots Better Than Standard Treatment An experimental device for removing blood clots in stroke patients dramatically outperformed the standard mechanical treatment, according to research presented by UCLA Stroke Center director Dr. Jeffrey L. Saver at the American Stroke Association's 2012 international conference in New Orleans. The SOLITAIRE Flow Restoration Device is among an entirely new generation of devices designed to remove blood clots from blocked brain arteries in patients experiencing stroke... How To Boost The Power Of Pain Relief, Without Drugs Placebos reduce pain by creating an expectation of relief. Distraction - say, doing a puzzle - relieves it by keeping the brain busy. But do they use the same brain processes? Neuromaging suggests they do. When applying a placebo, scientists see activity in the dorsolateral prefrontal cortex. That's the part of the brain that controls high-level cognitive functions like working memory and attention - which is what you use to do that distracting puzzle. Now a new study challenges the theory that the placebo effect is a high-level cognitive function. The authors - Jason T. Buhle, Bradford L...